Compounds > celastrol
Page last updated: 2024-09-03

celastrol and N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide

celastrol has been researched along with N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide in 1 studies

Compound Research Comparison

Studies
(celastrol)		Trials
(celastrol)		Recent Studies (post-2010)
(celastrol)		Studies
(N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide)		Trials
(N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide)		Recent Studies (post-2010) (N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide)
885174112011

Protein Interaction Comparison

ProteinTaxonomycelastrol (IC50)N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide (IC50)
Spike glycoproteinBetacoronavirus England 10.05
Replicase polyprotein 1abBetacoronavirus England 10.05
Transmembrane protease serine 2Homo sapiens (human)0.05
Calpain-1 catalytic subunitHomo sapiens (human)0.0041
Procathepsin LHomo sapiens (human)0.0194
Cathepsin BHomo sapiens (human)0.0041
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus0.05
Replicase polyprotein 1abHuman coronavirus 229E0.05
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus0.0402
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.0726
Cathepsin KHomo sapiens (human)0.0041
Spike glycoproteinSevere acute respiratory syndrome-related coronavirus0.05
Angiotensin-converting enzyme 2 Homo sapiens (human)0.05

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1

Other Studies

1 other study(ies) available for celastrol and N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide

ArticleYear
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021